| Mefou-et-Afamba | |
| Settlement Type: | Department |
| Mapsize: | 300px |
| Pushpin Map: | Cameroon#Africa |
| Pushpin Label Position: | bottom |
| Pushpin Mapsize: | 300 |
| Subdivision Type: | Country |
| Subdivision Name: |  Cameroon |
| Subdivision Type1: | Province |
| Subdivision Name1: | Centre Province |
| Subdivision Type2: | Capital |
| Subdivision Name2: | Mfou |
| Unit Pref: | Imperial |
| Area Total Km2: | 3358 |
| Population As Of: | 2001 |
| Population Total: | 89,805 |
| Population Blank1 Title: | Ethnicities |
| Timezone: | WAT |
| Utc Offset: | +1 |
Mefou-et-Afamba is a department of Centre Province in Cameroon. The department covers an area of 3,358 km and in 2001 had a total population of 89,805.[1] The capital of the department lies at Mfou.
The department is divided administratively into 8 communes, and in turn into villages:[2]