Mediastinal fibrosis explained

Mediastinal fibrosis
Field:	pulmonology
Causes:	histoplasmosis
Treatment:	glucocorticoids or immunosuppressants^[1]

Mediastinal fibrosis is characterized by invasive, calcified fibrosis centered on lymph nodes that block major vessels and airways. In Europe, this disease is exceptionally rare. More cases are seen in USA where the disease may often be associated with histoplasmosis.^{[2] [3]}

See also

• Mediastinitis

Notes and References

1. Rossi . Giovanni M. . Emmi . Giacomo . Corradi . Domenico . Urban . Maria L. . Maritati . Federica . Landini . Federica . Galli . Paola . Palmisano . Alessandra . Vaglio . Augusto . Idiopathic Mediastinal Fibrosis: a Systemic Immune-Mediated Disorder. A Case Series and a Review of the Literature . Clinical Reviews in Allergy & Immunology . June 2017 . 52 . 3 . 446–459 . 10.1007/s12016-016-8584-1. 27553003 . 46747661 .
2. Davis AM, Pierson RN, Loyd JE . Mediastinal fibrosis . Seminars in Respiratory Infections . 16 . 2 . 119–30 . 2001 . 11521244 . 10.1053/srin.2001.24242.
3. 460296 . 3715778 . 41 . 3 . Surgical treatment of idiopathic mediastinal fibrosis: report of five cases . Mitchell IM, Saunders NR, Maher O, Lennox SC, Walker DR . Thorax . 210–4 . 10.1136/thx.41.3.210. 1986 .