The Medellín small-eared shrew (Cryptotis medellinia) is a species of mammal in the family Soricidae. It is endemic to Colombia, where it is known from the northern parts of the Cordillera Occidental and Cordillera Central at elevations from . The species is found in montane forest and cultivated areas, and is subject to predation from the crab-eating fox. The specific name refers to the city of Medellín.