| Type: | Cardinal |
| Honorific-Prefix: | His Eminence |
| Medardo Joseph Mazombwe | |
| Archbishop Emeritus of Lusaka | |
| Archdiocese: | Lusaka |
| See: | Lusaka |
| Appointed: | 30 November 1996 |
| Term End: | 28 October 2006 |
| Predecessor: | Adrian Mung'andu |
| Successor: | Telesphore George Mpundu |
| Other Post: | Cardinal-Priest of Santa Emerenziana a Tor Fiorenza (2010-13) |
| Ordination: | 4 September 1960 |
| Consecration: | 7 February 1971 |
| Consecrated By: | Emmanuel Milingo, Firmin Courtemanche, M. Afr., and James Corby, S.J. |
| Cardinal: | 20 November 2010 |
| Created Cardinal By: | Pope Benedict XVI |
| Rank: | Cardinal-Priest |
| Birth Name: | Medardo Joseph Mazombwe |
| Birth Date: | 24 September 1931 |
| Birth Place: | Chundamira, Zambia |
| Death Place: | Lusaka, Zambia |
| Buried: | Lusaka Cathedral |
| Parents: | Joseph Adrian Mazombwe Eugenia Phiri |
| Alma Mater: | University of Lusaka |
Medardo Joseph Mazombwe (24 September 1931 – 29 August 2013) was a cardinal of the Catholic Church. He was Zambia's first indigenous cardinal.[1]
He was the former archbishop of the Roman Catholic Archdiocese of Lusaka (1996–2006)[2] and Bishop of the Roman Catholic Diocese of Chipata (1970–1996).
Pope Benedict XVI elevated Mazombwe to the status of Cardinal-Priest of Santa Emerenziana a Tor Fiorenza at a consistory on 20 November 2010.[3]
He held several senior positions in the local and regional church, such as Zambia Episcopal Conference president (1972–1975; 1988–1990; 1999–2002), and as chairman of the regional conferences under Association of Member Episcopal Conferences in Eastern Africa (A.M.E.C.E.A.) (1979–86). He was an ardent campaigner for Zambia's debt cancellation in the mid-1980s, through the Jubilee movement campaign and spearheaded several new developmental projects in many parts of the country including the Mumpanshya area of Chongwe.[4]
After his death, a foundation and a school were named after him in Chipata.[5]