| Official Name: | Mazanovo |
| Native Name: | Мазаново |
| Settlement Type: | Selo |
| Pushpin Map: | Russia Amur Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Amur Oblast |
| Subdivision Name3: | Mazanovsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +9:00 |
| Coordinates: | 51.6167°N 177°W[1] |
Mazanovo (Russian: Мазаново) is a rural locality (a selo) in Mazanovsky Selsoviet of Mazanovsky District, Amur Oblast, Russia. The population was 641 as of 2018.[2] There are 14 streets.
Mazanovo is located on the left bank of the Zeya River, 8 km west of Novokiyevsky Uval (the district's administrative centre) by road. Beloyarovo is the nearest rural locality.[3]