The Mayor of Roxbury was the head of the municipal government in Roxbury, Massachusetts. There was no Mayor of Roxbury until 1846 because up to that point Roxbury was still incorporated as a town. When Roxbury was annexed by the City of Boston in 1868, the position was abolished.
| Image | Mayor | Term | Party | ||
|---|---|---|---|---|---|
| 1 | John Jones Clarke | 1846 | None | ||
| 2 | Henry A. S. Dearborn | 1847–1851 | None | ||
| 3 | Samuel Walker | 1851–1853 | None | ||
| 4 | Linus Bacon Comins | 1854 | American Party | ||
| 5 | James Ritchie | 1855–1855 | None | ||
| 6 | John Sherburne Sleeper | 1856–1858 | None | ||
| 7 | Theodore Otis | 1859–1860 | None | ||
| 8 | William Gaston | 1861–1862 | Democratic | ||
| 9 | George Lewis | January 5, 1863 – January 5, 1868 | None | ||