| Mayor Luis Jorge Fontana Department | |
| Native Name Lang: | es |
| Settlement Type: | Department |
| Mapsize: | 180px |
| Pushpin Map Caption: | Location of Mayor Luis Jorge Fontana Department in Argentina |
| Coordinates: | -27.5833°N -103°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Argentina |
| Subdivision Type1: | Province |
| Subdivision Name1: | Chaco Province |
| Established Date: | 1910 (Villa Ángela) |
| Seat Type: | Head town |
| Seat: | Villa Ángela |
| Unit Pref: | Metric |
| Population Total: | 53,550 |
| Population Density Km2: | auto |
| Timezone1: | ART |
| Utc Offset1: | -3 |
| Postal Code: | H3540 |
| Area Code: | 03735 |
Mayor Luis Jorge Fontana is a southern department of Chaco Province in Argentina.
The provincial subdivision has a population of about 53,500 inhabitants in an area of 3,708 km2, and its capital city is Villa Ángela, which is located around 182 km from the provincial capital. The department takes its name from Luis Jorge Fontana, the first governor of Chubut and an explorer of the region.