| Official Name: | Mayo |
| Native Name: | มายอ |
| Native Name Lang: | th |
| Settlement Type: | District |
| Subdivision Type: | Country |
| Subdivision Name: | Thailand |
| Subdivision Type1: | Province |
| Subdivision Name1: | Pattani |
| Subdivision Type2: | Seat |
| Subdivision Type3: | Tambon |
| Subdivision Type4: | Muban |
| Established Title: | District established |
| Population Total: | 53070 |
| Population As Of: | 2005 |
| Blank Name Sec1: | Postal code |
| Blank Info Sec1: | 94140 |
| Blank Name Sec2: | Geocode |
| Blank Info Sec2: | 9405 |
| Timezone: | ICT |
| Utc Offset: | +7 |
| Coordinates: | 6.7186°N 101.41°W |
Mayo (Thai: มายอ, in Thai pronounced as /māː.jɔ̄ː/) is a district (amphoe) of Pattani province, southern Thailand.
The area of Mayo was originally part of Yaring district. In 1900 the district was established, then named Rako (ราเกาะ). When in the following year the district office in tambon Mayo was opened the district was renamed after its central tambon.
Neighboring districts are (from the north clockwise) Yaring, Panare, Thung Yang Daeng, and Yarang.
The district is divided into 13 sub-districts (tambons), which are further subdivided into 58 villages (mubans). Mayo is a township (thesaban tambon) which covers most parts of tambon Mayo. There are a further 10 tambon administrative organizations (TAO).
| No. | Name | Thai name | Villages | Pop. | |
|---|---|---|---|---|---|
| 1. | Mayo | มายอ | 3 | 4,468 | |
| 2. | Thanon | ถนน | 4 | 3,495 | |
| 3. | Trang | ตรัง | 4 | 3,014 | |
| 4. | Krawa | กระหวะ | 5 | 3,220 | |
| 5. | Lubo Yirai | ลุโบะยิไร | 8 | 9,880 | |
| 6. | La-nga | ลางา | 7 | 6,146 | |
| 7. | Kraso | กระเสาะ | 5 | 3,490 | |
| 8. | Ko Chan | เกาะจัน | 5 | 4,562 | |
| 9. | Pado | ปะโด | 4 | 4,506 | |
| 10. | Sakho Bon | สาคอบน | 3 | 2,896 | |
| 11. | Sakho Tai | สาคอใต้ | 4 | 1,885 | |
| 12. | Sakam | สะกำ | 4 | 3,880 | |
| 13. | Panan | ปานัน | 2 | 1,628 |