| Mayo-Louti | |
| Settlement Type: | Department |
| Mapsize: | 260px |
| Pushpin Label Position: | bottom |
| Pushpin Mapsize: | 300 |
| Subdivision Type: | Country |
| Subdivision Name: |  Cameroon |
| Subdivision Type1: | Province |
| Subdivision Name1: | North Province |
| Subdivision Type2: | Capital |
| Subdivision Name2: | Guider |
| Unit Pref: | Imperial |
| Area Total Km2: | 4161 |
| Population As Of: | 2001 |
| Population Total: | 334,312 |
| Population Blank1 Title: | Ethnicities |
| Timezone: | WAT |
| Utc Offset: | +1 |
| Coordinates: | 9.929°N 13.8795°W |
Mayo-Louti is a department of North Province in Cameroon. The department covers an area of 4161km2 and as of 2001 had a total population of 334,312.[1] The capital of the department is Guider.
The department is divided administratively into 3 communes and in turn into villages.