| Official Name: | Mayo, South Carolina |
| Settlement Type: | CDP |
| Mapsize: | 250px |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | South Carolina |
| Subdivision Type2: | County |
| Subdivision Name2: | Spartanburg |
| Unit Pref: | Imperial |
| Area Footnotes: | [1] |
| Area Total Km2: | 7.88 |
| Area Land Km2: | 7.88 |
| Area Water Km2: | 0.00 |
| Area Total Sq Mi: | 3.04 |
| Area Land Sq Mi: | 3.04 |
| Area Water Sq Mi: | 0.00 |
| Population As Of: | 2020 |
| Population Footnotes: | [2] |
| Population Total: | 1567 |
| Population Density Km2: | 198.98 |
| Population Density Sq Mi: | 515.29 |
| Timezone: | Eastern (EST) |
| Utc Offset: | -5 |
| Timezone Dst: | EDT |
| Utc Offset Dst: | -4 |
| Elevation Ft: | 889 |
| Coordinates: | 35.0881°N -81.8511°W |
| Postal Code Type: | ZIP code |
| Postal Code: | 29368 |
| Area Code: | 864 |
| Blank Name: | FIPS code |
| Blank Info: | 45-45430[3] |
| Blank1 Name: | GNIS feature ID |
| Blank1 Info: | 1231525 |
Mayo is a census-designated place (CDP) in Spartanburg County, South Carolina, United States. The population was 1,592 at the 2010 census.[4]
Mayo is located at 35.0881°N -81.8511°W (35.088031, -81.851034).[5]
According to the United States Census Bureau, the CDP has a total area of 3.1sqmi, all land.
As of the census of 2000, there were 1,842 people, 719 households, and 532 families residing in the CDP. The population density was 590.6/mi2. There were 773 housing units at an average density of 247.9/mi2. The racial makeup of the CDP was 97.29% White, 1.30% African American, 0.33% Native American, 0.49% Asian, 0.22% from other races, and 0.38% from two or more races. Hispanic or Latino of any race were 1.25% of the population.
There were 719 households, out of which 31.7% had children under the age of 18 living with them, 57.4% were married couples living together, 11.0% had a female householder with no husband present, and 26.0% were non-families. 22.4% of all households were made up of individuals, and 8.3% had someone living alone who was 65 years of age or older. The average household size was 2.56 and the average family size was 2.99.
In the CDP, the population was spread out, with 24.7% under the age of 18, 8.5% from 18 to 24, 30.5% from 25 to 44, 24.2% from 45 to 64, and 12.1% who were 65 years of age or older. The median age was 37 years. For every 100 females, there were 97.6 males. For every 100 females age 18 and over, there were 91.0 males.
The median income for a household in the CDP was $41,563, and the median income for a family was $47,045. Males had a median income of $31,997 versus $25,027 for females. The per capita income for the CDP was $16,465. About 9.7% of families and 12.8% of the population were below the poverty line, including 15.5% of those under age 18 and 11.0% of those age 65 or over.
It is in Spartanburg County School District 2.[6]