Maximiscin Explained

Maximiscin is a polyketide-shikimate chemical compound isolated from Tolypocladium that shows tumor growth suppression in an animal model.[1] The discovery of maximiscin was the result of a citizen scientist crowdsourcing project by the University of Oklahoma.[2] The soil sample which yielded maximiscin was sent by a woman from Salcha, Alaska.[3]

Notes and References

  1. 10.1055/s-0033-1348528 . Maximiscin, a Novel Shikimate-Polyketide-NRPS Hybrid Metabolite Obtained from Tolypocladium Sp. With Potent Antitumor Activities . 2013 . Du . L . Robles . AJ . King . JB . Powell . DR . Miller . AN . Mooberry . SL . Cichewicz . RH . Planta Medica . 79 . 10.
  2. 24285637 . 2013 . Du . L . Robles . AJ . King . JB . Powell . DR . Miller . AN . Mooberry . SL . Cichewicz . RH . Crowdsourcing Natural Products Discovery to Access Uncharted Dimensions of Fungal Metabolite Diversity . 10.1002/anie.201306549 . Angewandte Chemie International Edition in English . 804–9. 53 . 3 . 4028707.
  3. Web site: Crowdsourcing unearths promising anticancer compound . Julianne Wyrick . December 5, 2013 . chemistryworld.com . Royal Society of Chemistry.

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