| Mauvezin-sur-Gupie | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Mauvezin-sur-Gupie (Lot-et-Garonne).svg |
| Arrondissement: | Marmande |
| Canton: | Les Coteaux de Guyenne |
| Insee: | 47163 |
| Postal Code: | 47200 |
| Mayor: | Daniel Bordeneuve[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Val de Garonne Agglomération |
| Coordinates: | 44.5583°N 0.1644°W |
| Area Km2: | 15.60 |
Mauvezin-sur-Gupie (in French pronounced as /mov(ə)zɛ̃ syʁ ɡypi/; Occitan (post 1500);: Mauvesin) is a commune in the Lot-et-Garonne department in south-western France.