| Matsudaira Yoritake 松平 頼桓 | |
| Chamberlain, Upper 4th Rank | |
| Regent: | Tokugawa Yoshimune |
| Reg-Type: | Lord |
| Birth Date: | 23 July 1720 |
| Era Dates: | mid-Edo |
| Posthumous Name: | Kaikō |
was a Japanese daimyō of the Edo period, who ruled the Takamatsu Domain. Yoritake was the son of Matsudaira Yorihiro and great-grandson of Matsudaira Yorishige, lord of Takamatsu.
His descendant Yoritake Matsudaira, named after him, is a notable of Japanese Scouting and recipient of the Bronze Wolf.