| Matias Defensor | |
| Office: | Member of Philippine House of Representatives from Quezon City's 3rd congressional district |
| Term Start: | June 30, 2004 |
| Term End: | June 30, 2010 |
| Predecessor: | Ma. Theresa Defensor |
| Successor: | Jorge John B. Banal Jr. |
| Birth Name: | Matias Defensor |
| Birth Date: | 23 September 1943 |
| Party: | Independent (2015 - present) |
| Otherparty: | UNA (2012 - 2015) Lakas-CMD (2003 - 2012) |
| Spouse: | Florence T. Defensor |
| Children: | Mike Defensor Ma. Theresa Defensor |
Matias Defensor (born September 23, 1943) is a Filipino politician. A member of Lakas CMD, he represented the 3rd District of Quezon City in the House of Representatives of the Philippines for two terms from 2004 to 2010. He failed to win a third term as 2010 Elections, losing to Jorge Banal. He ran again for the same position in the 2013 elections but lost.
He is married to Florence Defensor. He is the father of Mike Defensor and Ma. Theresa Defensor, both former congressmen of the same district he represented. Mike represented the district for two terms (1995-1998 and 1998-2001) while Ma. Theresa for one term (2001-2004).
He graduated from University of the Philippines College of Law.