| Official Name: | Masterson Station |
| Settlement Type: | Neighborhood of Lexington, Kentucky |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Kentucky |
| Subdivision Type2: | County |
| Subdivision Name2: | Fayette |
| Subdivision Type3: | City |
| Subdivision Name3: | Lexington |
| Unit Pref: | Imperial |
| Area Total Km2: | 2.00983 |
| Area Total Sq Mi: | 0.776 |
| Population As Of: | 2021 |
| Population Total: | 33,696 |
| Population Density Sq Mi: | 1,193 |
| Timezone: | Eastern (EST) |
| Utc Offset: | -5 |
| Timezone Dst: | EDT |
| Utc Offset Dst: | -4 |
| Coordinates: | 38.096°N -84.542°W |
| Postal Code Type: | ZIP code |
| Postal Code: | 40511 |
| Area Code: | 859 |
| Website: | mastersonstation.org |
Masterson Station is a neighborhood in northwestern Lexington, Kentucky, United States. Its boundaries are Masterson Station Park on the west, Leestown Road to the south, Greendale Road to the east, and Spurr Road to the north.