Massie Creek is a stream in eastern Montgomery and southwestern Warren counties in the U.S. state of Missouri. It is a tributary of Loutre Slough.
The stream headwaters arise in eastern Montgomery County just to the south of Jonesburg and Interstate 70 at 38.8469°N -91.2992°W. The stream flows south to southwest into Warren County to its confluence with the Loutre Slough at 38.7331°N -91.3711°W within the Missouri River valley just east of the community of Case and after crossing under Missouri Route 94.[1]
Variant names include "Massas Creek", "Masses Creek", "Masseys Creek", and "Massies Creek". The creek most likely has the name of Peter Massie, an early settler.[2]