| Honorific-Prefix: | Rabbi |
| Masa'ud Raphael Alfasi | |
| Native-Name-Lang: | he |
| Main Work: | Mishḥa deRabuta |
| Death Date: | 1776 |
| Residence: | Tunisia |
| Children: | Solomon Ḥayyim |
| Occupation: | rabbi |
| Signature: | רבי מסעוד אלפסי.png |
Masa'ud Raphael Alfasi (died 1776) was a Tunisian rabbi.
He is the author of "Mishḥa deRabuta" (Oil of Anointing), a work containing notes on all four sections of Rabbi Joseph Karo's "Shulchan Aruch"[1] (Leghorn, 1805). He was assisted by his two learned sons, Solomon (died 1801) and Ḥayyim (died 1783), the former being the author of a similar work, "Kerub Mimshaḥ" (The Anointed Cherub), Leghorn, 1859.