| Clubname: | Marquense |
| Fullname: | Club Deportivo Marquense |
| Nickname: | Los Leones de San Marcos (The Lions of San Marcos) |
| Founded: | 1 April 1958; 66 years ago |
| Ground: | Estadio Marquesa de la Ensenada |
| Capacity: | 11,000 |
| Chairman: | Rolando Pineda |
| Manager: | Érick González |
| League: | Liga Nacional |
| Season: | Clausura 2024 |
| Position: | Group A 4th (Champions) |
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Club Deportivo Marquense, or simply Marquense, is a Guatemalan football club based in San Marcos, Department of San Marcos. They compete in the Liga Nacional, the top tier of Guatemalan football following promotion from qualifying for back to back finals in the 2023-24 Primera División season and winning the Clausura 2024. Their home venue is at the Estadio Marquesa de la Ensenada.
The club was founded in 1 April 1958, and were promoted to the then Liga Mayor "A" in 1962, remaining in the First Division until 1966, when they finished last or relegation place. They were relegated down as the Segunda Division (third tier in the country), before earning promotion to the Primera División de Ascenso in the 1990s. After more than three decades competing in lower divisions, the team was promoted to the Liga Nacional in May 2000, and they reached the semi-finals of the 2004 Apertura tournament. They finished second in the 2006 Clausura tournament, their best result ever, reaching the final and eliminated by the defending champion Municipal.
Marquense qualified to the UNCAF Club Tournament for the first time in their history after finishing above the loser of the 2005 Apertura final, Comunicaciones, in the overall standings. The team reached the semi-finals of the 2006 UNCAF tournament, where they lost to Costa Rican club Puntarenas, but after beating Victoria of Honduras in the third place match on a 4–1 aggregate, they were able to reach the CONCACAF Champions' Cup for the first time in their history. Marquense played Pachuca, the Mexican First Division defending champions, in the 2007 CONCACAF Champions' Cup quarter-finals, with Pachuca winning the first leg 2–0 at home on February 22, 2007 and 1–0 in San Marcos on 28 February 2007, thus eliminating the Guatemalan team on a 3–0 aggregate.
In the 2007 Clausura tournament, Marquense reached the final, facing rivals Xelajú, who won the title on a 4–2 aggregate score. It was the first time since 1980 that two teams from out of Guatemala City finished as champions and runner-up.
Marquense shares a common rivalry with Xelajú called the Clásico de Occidente and with Malacateco known as the Derbi de San Marcos.
1 appearance
2006–07 - Third Place
| Year | Opponent | 1st leg | 2nd leg | |
|---|---|---|---|---|
| 2006–07 | 2–0 | 1–1 | ||
| 2006–07 | 1–1 | 1–0 | ||
| 2006–07 | 0–2 | 0–0 | ||
| 2006–07 | 3–0 | 1–1 |
1 appearance
2006–07 - Quarter-finals
4 – 
Marcos Menaldo, defender (2017-2022)