| Mark Twain/I-70 Industrial | |
| Type: | Neighborhood of St. Louis |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Missouri |
| Subdivision Type3: | City |
| Subdivision Name3: | St. Louis |
| Parts Type: | Wards |
| Parts Style: | para |
| P1: | 22 |
| Leader Title: | Aldermen |
| Population Total: | 902 |
| Population As Of: | 2020 |
| Population Footnotes: | [1] |
| Area Total Sq Mi: | 1.21 |
| Population Density Sq Mi: | auto |
| Postal Code Type: | ZIP code(s) |
| Postal Code: | Part of 63115, 63120 |
| Area Code Type: | Area code(s) |
| Area Code: | 314 |
| Website: | stlouis-mo.gov |
Mark Twain/I-70 Industrial is a neighborhood of St. Louis, Missouri. It is bound by I-70 to the north, North Kingshighway to the east, Natural Bridge Road to the south, and the city limit to the west.
In 2020 Mark Twain/I-70 Industrial's racial makeup was 92.5% Black, 3.7% White, 0.2% Asian, 0.1% American Indian, 3.0% Two or More Races, and 0.6% Some Other Race. 1.3% of the population was of Hispanic or Latino origin.[2]