| Mario Francisco Guillén Guillén | |
| Birth Date: | 1970 10, df=yes |
| Birth Place: | Comitán, Chiapas, Mexico |
| Occupation: | Deputy |
| Party: | PVEM |
Mario Francisco Guillén Guillén (born 4 October 1970) is a Mexican politician affiliated with the PVEM. He currently serves, since 16 July 2013, as Deputy of the LXII Legislature of the Mexican Congress representing Chiapas.[1]