| Mario Agnes | |
| Birth Date: | 1931 12, df=y |
| Birth Place: | Serino, Italy |
| Death Place: | Vatican City |
Mario Agnes (6 December 1931, Serino – 9 May 2018, Vatican City) was an Italian journalist. In 1984 he was appointed editor-in-chief of L'Osservatore Romano by Pope John Paul II. He held the position until his retirement in 2007, at which point he was honored by Pope Benedict XVI.[1]