Marie-Josée Jacobs (born 22 January 1950 in Marnach) is a politician from Luxembourg.
Jacobs has been active in the Lëtzebuerger Chrëschtleche Gewerkschaftsbond (LCGB). In 1984 she became a parliamentarian. Since 1992 she has served in the Cabinet as Minister of Family, Integration, and Equal Opportunities. Jacobs is a member of the Christian Social People's Party.