| Marie Claire de Bauffremont | |
| Countess of Fleix | |
| Full Name: | Marie Claire de Bauffremont |
| Birth Date: | Birth July 11 , 1618 |
| Death Date: | July 29 , 1680 (aged 62) |
| Death Place: | Paris, France |
| Spouse: | Jean Baptiste Gaston de Foix, Count of Fleix (1637) |
| Issue: | Jean Baptiste Gaston, Duke of Randan |
| Mother: | Marie Catherine de La Rochefoucauld |
| Father: | Henri de Bauffremont, Marquis of Senecey |
Marie Claire de Bauffremont (July 11, 1618– July 29 , 1680) was a French courtier. She served as Première dame d'honneur to the queen dowager of France, Anne of Austria, from 1643 until 1666.
She was the daughter of Henri de Bauffremont, marquise de Senecey, and Marie-Catherine de Senecey, and married to Jean Baptiste Gaston de Foix, comte de Fleix (1617–1646), in 1637. Her mother was a favorite of queen Anne who had been banished from court by Cardinal Richelieu, and when queen Anne became regent in 1643, she appointed Marie-Catherine de Senecey royal governess and her daughter to the office of Première dame d'honneur.
By the request of her mother, she inherited the title duchess de Randan after her. She also inherited the title marquise de Sennecey after her childless brother in 1641.