| Mariano Comense | |
| Native Name Lang: | it |
| Address: | Piazza A. Diaz 3 |
| Borough: | Mariano Comense, Como, Lombardy |
| Country: | Italy |
| Map Type: | Italy Lombardy#Italy North#Italy |
| Coordinates: | 45.6936°N 9.1814°W |
| Line: | Milan–Asso |
| Train Operators: | Trenord |
| Platform: | 3 |
| Operator: | Ferrovienord |
Mariano Comense railway station is a railway station in Italy. Located on the Milan–Asso railway, it serves the town of Mariano Comense.
Mariano Comense is terminus of a few trains of line S2 of the Milan suburban railway network, and served as well by the regional trains Milan–Asso. All this trains are operated by the lombard railway company Trenord.