| Maria de Cardona | |
| Birth Date: | 1509 |
| Birth Place: | Naples, Kingdom of Naples |
| Death Date: | 9 March 1563 |
| Death Place: | Naples, Kingdom of Naples |
| Nationality: | Italian |
| Occupation: | Noblewoman |
Maria de Cardona or Maria Folch de Cardona (1509, probably in Naples - 9 March 1563, Naples) was an Italian noblewoman and patron of the arts. She was from the Folch de Cardona family. de Cardona was the Countess of Avellino, Marquise of Padula, and Baroness of Candida and habitually lived in the Irpinia castle.