| María Elena Calle | |
| Birth Date: | 25 July 1975 |
| Height: | 162 cm |
| Weight: | 54 kg |
| Sport: | Track and field |
| Event: | Marathon |
| Coach: | Julian Spooner Ben Rosario |
| Pb: | 2:42:19 (2016) |
| Show-Medals: | yes |
María Elena Calle (born 25 July 1975) is an Ecuadorian marathon runner. She placed 99th at the 2016 Olympics.
Calle took up running in 1984, but ran her first marathon only in 2011. She has a degree in occupational therapy from Virginia Commonwealth University where she competed for the VCU Rams track and field team.[1] She is married to Brad Lowery and works as a therapist in the United States.