| Margherita Gonzaga | |
| Noble Family: | Gonzaga |
| Marquise of Ferrara | |
| Birth Date: | 1418 |
| Birth Place: | Mantua |
| Death Date: | 7 July 1439 |
| Death Place: | Governolo |
| Resting Place: | Mantua |
| Spouse: | Leonello d'Este, Marquis of Ferrara |
| Issue: | Niccolò d'Este (Niccolò di Leonello) |
| Father: | Gianfrancesco I Gonzaga, Marquess of Mantua |
| Mother: | Paola Malatesta |
Margherita Gonzaga, Marquise of Ferrara (1418–1439) was a noblewoman of the family House of Gonzaga from Mantua in modern-day Italy. She was the child of Gianfrancesco I Gonzaga, Marquess of Mantua[1] and Paola Malatesta.[2] In 1435 she became the first wife of Leonello d'Este, Marquis of Ferrara[3] [4] through whom she earned the title Marquise of Ferrara. The artist Pisanello gave a wedding gift of a painting of Julius Caesar. This marriage brought an alliance between the House of Gonzaga of Mantua and the House of Este of Ferrara.[5] They had a son Niccolò, who is also known as Niccolò di Leonello to avoid confusion with his grandfather Niccolò III d'Este.[6]