| Margarita Villaescusa Rojo | |
| Birth Date: | 1964 10, df=yes |
| Birth Place: | Culiacán, Sinaloa, Mexico |
| Occupation: | Senator |
| Party: | PRI |
Margarita Villaescusa Rojo (born 14 October 1964) is a Mexican politician affiliated with the PRI. As of 2013 she served as Senator of the LXI Legislature of the Mexican Congress representing Sinaloa as replacement of Mario López Valdez.[1]