| Margaret of Blois | |
| Noble Family: | |
| Father: | Theobald V, Count of Blois |
| Mother: | Alice of France |
| Spouse: | Hugh of Oisy Otto I, Count of Burgundy Walter II of Avesnes |
| Issue: | Joanna I, Countess of Burgundy Beatrice II, Countess of Burgundy Mary, Countess of Blois |
| Death Date: | 12 July |
| Death Place: | Besançon |
Margaret of Blois (French: Marguerite; died 1230) was suo jure Countess of Blois in France from 1218 to 1230. From 1190 to 1200, she was the countess consort of the County of Burgundy and then regent for her daughters from 1200 until 1208.
She was daughter of Theobald V of Blois and Alix of France.
Margaret married three times. Her first marriage was to Hugh of Oisy, Lord of Montmirail. Her second husband was Otto I, Count of Burgundy, with whom she had two daughters:
Finally, she married Walter II of Avesnes, they had: