| Marcelo de Souza | |
| Fullname: | Marcelo Alejandro De Souza |
| Birth Date: | 30 September 1975 |
| Birth Place: | Montevideo, Uruguay |
| Height: | 1.85 m |
| Position: | Centre Back |
| Years1: | 1993–1995 |
| Years2: | 1995–2001 |
| Years3: | 2001 |
| Years4: | 2002–2003 |
| Years5: | 2003–2004 |
| Years6: | 2004–2005 |
| Years7: | 2005 |
| Years8: | 2005–2006 |
| Years9: | 2006 |
| Years10: | 2006–2007 |
| Years11: | 2007 |
| Years12: | 2009–2011 |
| Years13: | 2011–2012 |
| Years14: | 2012–2013 |
| Clubs14: | Canadian |
| Caps1: | 0 |
| Goals1: | 0 |
| Caps2: | 107 |
| Goals2: | 22 |
| Caps3: | 23 |
| Goals3: | 4 |
| Caps4: | 50 |
| Goals4: | 7 |
| Caps5: | 12 |
| Goals5: | 1 |
| Caps6: | 10 |
| Goals6: | 0 |
| Caps7: | 11 |
| Goals7: | 0 |
| Caps8: | 17 |
| Goals8: | 3 |
| Caps9: | 10 |
| Goals9: | 2 |
| Caps10: | 0 |
| Goals10: | 0 |
| Caps11: | 5 |
| Goals11: | 1 |
| Caps12: | 23 |
| Goals12: | 0 |
| Caps13: | 10 |
| Goals13: | 0 |
| Nationalyears1: | 2004 |
| Nationalteam1: | Uruguay |
| Nationalcaps1: | 2 |
| Nationalgoals1: | 1 |
| Pcupdate: | 3 May 2016 |
Marcelo Alejandro De Souza (born September 30, 1975) is a Uruguayan footballer currently playing as a midfielder for Boston River in the Uruguayan Segunda División.