| María Soledad Barría | |
| Birth Date: | 1953 10, df=y |
| Birth Place: | Osorno, Chile |
| Office: | Minister of Health |
| President: | Michelle Bachelet |
| Term Start: | 11 March 2006 |
| Term End: | 28 October 2008 |
| Predecessor: | Pedro García Aspillaga |
| Successor: | Álvaro Erazo |
| Party: | Socialist Party |
| Alma Mater: | University of Chile |
| Occupation: | Politician |
| Profession: | Physician |
| Parents: | Daniel Barría María Iroume |
| Spouse: | Oscar Neira (1978−present) |
| Children: | Two |
María Soledad Barría Iroume (born 27 October 1953) is a Chilean physician who served as minister during the first government of Michelle Bachelet (2006–2010).[1]