| María Cristina Arango | |
| Office: | First Lady of Colombia |
| Term Label: | In role |
| President: | Misael Pastrana Borrero |
| Predecessor: | Cecilia de la Fuente de Lleras |
| Successor: | Cecilia Caballero Blanco |
| Birth Date: | 15 October 1928 |
| Birth Place: | Bogotá, D.C., Colombia |
| Death Place: | Bogotá, D.C., Colombia |
| Nationality: | Colombian |
| Party: | Liberal |
María Cristina Arango Vega (15 October 1928[1] – 15 September 2017) was the First Lady of Colombia from 1970 to 1974 as the wife of the 23rd President of Colombia, Misael Pastrana Borrero.[2] Arango was also the mother of the 30th President Andrés Pastrana.
María Cristina was born in Bogotá to, a Liberal party politician and presidential candidate,[3] and his wife María Vega Jaramillo.[2]
In 1946, while her father was serving as Ambassador of Colombia to the Holy See, she met Misael Pastrana Borrero, who was working as a diplomat in the embassy.[4] They got engaged that year and married on 24 February 1951 at the Saint Bartholomew School's Madonna Della Strada Chapel in Bogotá.[5] Together they had four children, Juan Carlos, Andrés, Jaime, and María Cristina. She died in Bogota on 15 September 2017 at the age of 88.[6]