| Established: | 1923 |
| Motto: | Soar High Mapa High, Excellence Forever |
| Nickname: | VMHS, Mapa |
| Principal: | Mr. Edmund G. Villareal |
| City: | 300 San Rafael St. San Miguel |
| State: | Manila |
| Country: | Philippines |
| Coordinates: | 14.5979°N 120.9921°W |
| Free Label: | Hymn |
| Free: | "V.Mapa High School Hymn" |
| Grades: | 7 to 12 |
| Students: | approx. 9,000 |
| Campus: | Urban |
| Colors: | Blue, White |
| Mediums: | English, Filipino |
| Type: | Public with Special Science |
| Affiliations: | Division of City Schools-Manila |
| Newspaper: | The Mapazette, Ang Gabay and Ang Likha |
Victorino Mapa High School (Filipino; Pilipino: Mataas na Paaralang Victorino Mapa) (formerly Manila East High School), situated in San Miguel, Manila, is one of the oldest public high schools in the city. It has produced a list of successful graduates in various fields since its foundation in 1923.
Along with Manila Science High School, Ramon Magsaysay High School, Manuel Roxas High School, Arellano (Manila North) High School, and Araullo High School, Victorino Mapa offers rigorous Special Science courses to selected top students. The institution is considered one of the top schools in Manila in terms of its performance in achievement tests and competitions. In 2007, VMHS was named one of the cleanest schools in Manila.
Victorino Mapa High School opened its first classes (Manila East High School) as one of the four schools in City of Manila together with Torres High School (Manila South High School) and Arellano (Manila North) High School in June 1923.
The school has been under the administration of principals since it was founded in June 1923. The three of these were Americans namely, John Carl, Sarah M. England and James Burns. The first Filipino principal was Indalecio Madamba, installed in 1951. In his term, the Parents-Teachers Association was organized and succession of principals took over, after Madamba retired in May 1956.
Student population of VMHS traditionally come from the district of San Miguel, Quiapo, Sampaloc and Santa Mesa consisting of family homogenous in economic and social standards with a few transferees from provinces and graduate from Padre Burgos Elementary School (PBES) of Principal Ms. Trinidad R. Galang. in Altura St. Sta Mesa, Manila.
The school once had a biggest student population of 11,481 with a faculty of 488.