| Manya Krobo District | |
| Settlement Type: | Former District |
| Pushpin Map: | Ghana |
| Pushpin Map Caption: | Location of Manya Krobo District within Eastern |
| Subdivision Type: | Country |
| Subdivision Name: |  Ghana |
| Subdivision Type1: | Region |
| Subdivision Type2: | Capital |
| Subdivision Name2: | Odumase |
| Leader Title: | District Executive |
| Area Total Km2: | 819 |
| Timezone: | GMT |
| Utc Offset: | +0 |
| Coordinates: | 6.1021°N -0.5334°W |
| Iso Code: | GH-EP-MK |
Manya Krobo District is a municipality located in Eastern Region, Ghana. Originally created as an ordinary district assembly in 1988, which was created from the former Kaoga District Council. However on 29 February 2008, it was split off into two new districts: Lower Manya Krobo District (which it was elevated to municipal district assembly status on 6 February 2012; capital: Odumase) and Upper Manya Krobo District (capital: Asesewa). The municipal assembly is located in the eastern part of Eastern Region and has Odumase as its capital town.
Notably, professional footballer Thomas Partey is a chief of the Manya Krobo people.