| Manuel Méndez | |
| Term Start: | 1 February 1872 |
| Term End: | 1 September 1872 |
| Predecessor: | Position vacant (José María Parrilla in 1871) |
| Successor: | Position vacant (Santiago González Portillo in 1876) |
| Term Start1: | 10 May 1872 |
| Term End1: | 16 June 1872 Acting President |
| Birth Date: | Unknown |
| Death Date: | 1 September 1872 |
| Occupation: | Politician |
Manuel Méndez (died 1 September 1872) was a Salvadoran politician who served as vice president of El Salvador between February and his assassination in September 1872, as well as serving acting president between May and June 1872. He also served as Minister of the Interior.[1]
Méndez was elected as vice president of El Salvador and assumed office on 1 February 1872, serving under President General Santiago González Portillo. On 10 May, he became acting president on behalf of González Portillo, while he commanded an army against Honduran President José María Medina. González Portillo resumed his presidential duties on 16 June.
At 9:00 p.m. on 1 September 1872, Méndez was assassinated in San Salvador's main plaza.