| Official Name: | Municipality of Manoel Urbano |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Brazil |
| Subdivision Type: | Country |
| Subdivision Name: | Brazil |
| Subdivision Type1: | State |
| Subdivision Name1: | Acre |
| Leader Title: | Mayor |
| Leader Name: | José Altanízio Taumaturgo Sá (PMDB) |
| Unit Pref: | Imperial |
| Area Total Km2: | 9387 |
| Population As Of: | 2020 est [1] |
| Population Total: | 9,581 |
| Population Blank1 Title: | Ethnicities |
| Timezone: | ACT |
| Utc Offset: | -5 |
| Coordinates: | -8.8389°N -69.26°W |
Manoel Urbano (pronounced as /pt/) is a municipality located in the center-western region of the Brazilian state of Acre.As of 2010 it was one of the poorest municipalities in Brazil, with a low Human Development Index.
Manoel Urbano is in the state of Acre, the Vale do Acre mesoregion and the Sena Madureira microregion.It is from the state capital, Rio Branco, along the BR-364, which is paved to the municipality.It is bounded on the north by the state of Amazonas, on the south and east by the municipality of Sena Madureira, on the west by the municipality of Santa Rosa do Purus, on the northwest by the municipality of Feijó and on the southwest by Peru.Its area is .
The municipality contains 2% of the Cazumbá-Iracema Extractive Reserve, established in 2002 to support sustainable use of the natural resources by the traditional population.It also contains about 66% of the Chandless State Park, created in 2004, which protects an area of rainforest with bamboos that contains various endemic species of flora and fauna.
The history of European settlement dates to the end of the 19th century when two brothers, João Moaco and Zé Moaco, founded the Colocação Tabocal settlement on the right bank of the Purus River. At that time supplies and produce were shipped via the Purus by boats and smaller vessels from the ports of Belém and Manaus.One summer a boat named "Castelo" was stranded during the dry season, and was not floated until the next rainy season.The residents began to call the area "Castelo".In 1936 the residents asked the state government to make the settlement a town named after Manoel Urbano, an Amazonian mestizo from the Manacapurú region who had explored the Purus River.In the territorial division of 31 December 1936 the region was the Castelo district of the Sena Madureira municipality.On 1 March 1963 the municipality of Manoel Urbano was separated from Sena Madureira.
In the 2010 Census, its population was 7,981, divided between 5,278 urban and 2,703 rural.As of 2010 the municipality ranked 5186 out of 5565 of Brazilian municipalities on the Human Development Index.The overall index was 0.551. Income was 0.586, longevity was 0.767 and education was 0.373.As of 1 July 2014 the estimated population was 8,514. In 2020, IBGE estimated the population at 9,581.