Mannosylfructose-phosphate phosphatase explained

Mannosylfructose-phosphate phosphatase
Ec Number:	3.1.3.79

Mannosylfructose-phosphate phosphatase (EC 3.1.3.79, mannosylfructose-6-phosphate phosphatase, MFPP) is an enzyme with systematic name β-D-ructofuranosyl-α-D-mannopyranoside-6^F-phosphate phosphohydrolase.^[1] This enzyme catalyses the following chemical reaction

β-D-fructofuranosyl-α-D-mannopyranoside 6^F-phosphate + H₂O

\rightleftharpoons
β-D-fructofuranosyl-α-D-mannopyranoside + phosphate

This enzyme, from the soil proteobacterium and plant pathogen Agrobacterium tumefaciens strain C58, requires Mg²⁺ for activity.

Notes and References

1. Torres LL, Salerno GL . A metabolic pathway leading to mannosylfructose biosynthesis in Agrobacterium tumefaciens uncovers a family of mannosyltransferases . Proceedings of the National Academy of Sciences of the United States of America . 104 . 36 . 14318–23 . September 2007 . 17728402 . 1964871 . 10.1073/pnas.0706709104 . free .