Mannosyl-3-phosphoglycerate phosphatase explained

mannosyl-3-phosphoglycerate phosphatase
Ec Number:	3.1.3.70
Go Code:	0050531

The enzyme mannosyl-3-phosphoglycerate phosphatase^[1] (EC 3.1.3.70) catalyzes the reaction

2-O-(α-D-mannosyl)-3-phosphoglycerate + H₂O = 2-O-(α-D-mannosyl)-D-glycerate + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is 2-O-(α-D-mannosyl)-3-phosphoglycerate phosphohydrolase.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and .

Notes and References

1. Empadinhas N, Marugg JD, Borges N, Santos H, da Costa MS . 2001 . Pathway for the synthesis of mannosylglycerate in the hyperthermophilic archaeon Pyrococcus horikoshii. Biochemical and genetic characterization of key enzymes . J. Biol. Chem. . 276 . 43580 - 8 . 11562374 . 10.1074/jbc.M108054200 . 47 . free .