Mannitol dehydrogenase explained
| mannitol dehydrogenase |
| Ec Number: | 1.1.1.255 |
| Cas Number: | 144941-29-7 |
| Go Code: | 0046029 |
In enzymology, a mannitol dehydrogenase is an enzyme that catalyzes the chemical reaction
D-mannitol + NAD+
D-mannose + NADH + H
+Thus, the two substrates of this enzyme are D-mannitol and NAD+, whereas its 3 products are D-mannose, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is mannitol:NAD+ 1-oxidoreductase. Other names in common use include MTD, and NAD+-dependent mannitol dehydrogenase.
References
- Stoop JM, Pharr DM . 1992 . Partial purification and characterization of mannitol: mannose 1-oxidoreductase from celeriac (Apium graveolens var. rapaceum) roots . Arch. Biochem. Biophys. . 298 . 612 - 9 . 1416989 . 10.1016/0003-9861(92)90456-7 . 2 .
- Stoop JM, Williamson JD, Conkling MA, Pharr DM . 1995 . Purification of NAD-dependent mannitol dehydrogenase from celery suspension cultures . Plant Physiol. . 108 . 1219 - 25 . 7630943 . 10.1104/pp.108.3.1219 . 3 . 157476 .
- Williamson JD, Stoop JM, Massel MO, Conkling MA, Pharr DM . 1995 . Sequence analysis of a mannitol dehydrogenase cDNA from plants reveals a function for the pathogenesis-related protein ELI3 . Proc. Natl. Acad. Sci. U.S.A. . 92 . 7148 - 52 . 7638158 . 10.1073/pnas.92.16.7148 . 16 . 41296 . free .
- Stoop, JMH, Chilton WS, Pharr DM . 1996 . Substrate specificity of the NAD-dependent mannitol dehydrogenase from celery . . 43 . 1145 - 1150 . 10.1016/S0031-9422(96)00423-2 . 6 .
See also
