| mannitol 2-dehydrogenase (NADP+) | |
| Ec Number: | 1.1.1.138 |
| Cas Number: | 37250-68-3 |
| Go Code: | 0050085 |
In enzymology, a mannitol 2-dehydrogenase (NADP+) is an enzyme that catalyzes the chemical reaction
D-mannitol + NADP+
\rightleftharpoons
Thus, the two substrates of this enzyme are D-mannitol and NADP+, whereas its 3 products are D-fructose, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-mannitol:NADP+ 2-oxidoreductase. This enzyme is also called mannitol 2-dehydrogenase (NADP+). This enzyme participates in fructose and mannose metabolism.
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .