| Manitou Springs High School | |
| Address: | 401 El Monte Place |
| City: | Manitou Springs |
| State: | Colorado |
| Zipcode: | 80829 |
| Country: | United States |
| Coordinates: | 38.8558°N -104.9033°W |
| Schooltype: | Public high school |
| District: | Manitou Springs 14 |
| Ceeb: | 060970 |
| Principal: | Anna Conrad |
| Teaching Staff: | 28.60 |
| Grades: | 9–12 |
| Enrollment: | 492 |
| Enrollment As Of: | 2018–2019 |
| Ratio: | 17.20 |
| Colors: | Green and gold |
| Athletics Conference: | CHSAA |
| Mascot: | Mustang |
| Feeder Schools: | Manitou Springs Middle School |
Manitou Springs High School (MSHS) is a public high school in Manitou Springs, Colorado, United States. It is the only high school in the Manitou Springs School District 14. The high school has the highest graduation rate in the Pikes Peak Region and one of the lowest remediation rates for students entering college. Manitou teachers give students the option to prepare for the Advanced Placement testing in multiple subjects.