Maltose-transporting ATPase explained
maltose-transporting ATPase |
Ec Number: | 3.6.3.19 |
Go Code: | 0015423 |
In enzymology, a maltose-transporting ATPase is an enzyme that catalyzes the chemical reaction
ATP + H2O + maltoseout
ADP + phosphate + maltosein
The 3 substrates of this enzyme are ATP, H2O, and maltose, whereas its 3 products are ADP, phosphate, and maltose.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (maltose-importing). This enzyme is a member of the ABC Transporter family.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and .
References
- Higgins CF . 1992 . ABC transporters: from microorganisms to man . Annu. Rev. Cell Biol. . 8 . 67 - 113 . 1282354 . 10.1146/annurev.cb.08.110192.000435 .
- Dassa E, Muir S . 1993 . Membrane topology of MalG, an inner membrane protein from the maltose transport system of Escherichia coli . Mol. Microbiol. . 7 . 29 - 38 . 8437518 . 10.1111/j.1365-2958.1993.tb01094.x . 1 . 86377074 .
- Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH . 1995 . Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases . Res. Microbiol. . 146 . 271 - 8 . 7569321 . 4 . 10.1016/0923-2508(96)81050-3. free .
- Saier MH Jr . 1998 . Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya . Adv. Microb. Physiol. . Advances in Microbial Physiology . 40 . 81 - 136 . 9889977 . 10.1016/S0065-2911(08)60130-7 . 9780120277407 .
- Griffiths JK . Sansom CE . The Transporter Factsbook, Academic Press, San Diego, 1998 .