Malnutrition–inflammation complex explained

Differential:	Chronic heart failure

Malnutrition–inflammation complex (syndrome) (MICS), also known as malnutrition–inflammation–cachexia syndrome, is a common condition in chronic disease states such as chronic kidney disease (where it is also known as uremic malnutrition or protein–energy malnutrition) and chronic heart failure.

The MICS is believed to be a cause of survival paradoxes seen in these distinct patient populations, also known as reverse epidemiology populations.^[1]

Further reading

• Anand . Nithya . The Malnutrition Inflammation Complex Syndrome-The Micsing Factor in the Perio-Chronic Kidney Disease Interlink . Journal of Clinical and Diagnostic Research . JCDR Research and Publications . 2013 . 7 . 4 . 763–767 . 2249-782X . 10.7860/jcdr/2013/5329.2907 . 23730672 . 3644470 . none.
• Kalantar-Zadeh . Kamyar . Ikizler . T.Alp . Block . Gladys . Avram . Morrel M. . Kopple . Joel D. . Malnutrition-inflammation complex syndrome in dialysis patients: causes and consequences . American Journal of Kidney Diseases . Elsevier BV . 42 . 5 . 2003 . 0272-6386 . 10.1016/j.ajkd.2003.07.016 . 864–881 . 14582032 . 26457475 . none.

Notes and References

1. Kalantar-Zadeh . Kamyar . Ikizler . T.Alp . Block . Gladys . Avram . Morrel M. . Kopple . Joel D. . Malnutrition-inflammation complex syndrome in dialysis patients: causes and consequences . American Journal of Kidney Diseases . November 2003 . 42 . 5 . 864–881 . 10.1016/j.ajkd.2003.07.016 . 14582032 . 26457475 .