Proliferating trichilemmal cyst explained
| Proliferating trichilemmal cyst |
| Synonyms: | Pilar tumor, proliferating follicular cystic neoplasm, proliferating pilar tumor, and proliferating trichilemmal tumor |
| Field: | Dermatology |
Proliferating trichilemmal cysts (also known as a pilar tumor, proliferating follicular cystic neoplasm, proliferating pilar tumor, and proliferating trichilemmal tumor)[1] is a cutaneous condition, characterized by proliferations of squamous cells forming scroll-like structures.[1] [2]
Signs and symptoms
The tumors, which are typically found in regions like the scalp with a high density of hair follicles, can be solid or solid cystic. Proliferating trichilemmal cyst frequently manifests clinically as a subcutaneous nodule that gradually grows into a big nodular mass. Rapid growth in some cases may be a sign of malignant development into cancer.[3]
Diagnosis
Histologically, Proliferating trichilemmal cysts are distinguished by trichilemmal keratinization, which is the sudden change from nucleated epithelium to anucleated keratinized cells without a granular layer. The differential diagnosis include trichilemmal cyst and Turban tumor.[4]
Treatment
Surgical excision is the treatment of choice for proliferating trichilemmal cysts.
Epidemiology
Proliferating trichilemmal cysts make up 0.1% of all skin tumors.[5] Most patients with these tumors are older women, and 90% of patients with these lesions appear on the scalp.[6]
See also
Further reading
- Kearns-Turcotte . Sélia . Thériault . Mimi . Blouin . Marie-Michèle . Malignant proliferating trichilemmal tumors arising in patients with multiple trichilemmal cysts: A case series . JAAD Case Reports . Elsevier BV . 22 . 2022 . 2352-5126 . 10.1016/j.jdcr.2022.01.033 . 42–46 . 35310136 . 8924508 . none.
- Sharma . Reena . Verma . Prashant . Yadav . Pravesh . Sharma . Sonal . Proliferating trichilemmal tumor of scalp: Benign or malignant, A dilemma . Journal of Cutaneous and Aesthetic Surgery . Medknow . 5 . 3 . 2012 . 0974-2077 . 10.4103/0974-2077.101394 . free . 213 . none. 3483585 .
External links
Notes and References
- Book: Rapini, Ronald P. . Bolognia, Jean L. . Jorizzo, Joseph L. . Dermatology: 2-Volume Set . Mosby . St. Louis . 2007 . 978-1-4160-2999-1 .
- Book: James, William D. . Berger, Timothy G.. Andrews' Diseases of the Skin: Clinical Dermatology . Saunders Elsevier . 2006 . 0-7216-2921-0 . etal.
- Valerio . Ediel . Parro . Fernando Henrique Sgarbi . Macedo . Mariana Petaccia de . Pinto . Clovis Antonio Lopes . Proliferating trichilemmal cyst with clinical, radiological, macroscopic, and microscopic correlation . Anais Brasileiros de Dermatologia . FapUNIFESP (SciELO) . 94 . 4 . 2019 . 1806-4841 . 10.1590/abd1806-4841.20198199 . 452–454. 31644620 . 7007035 .
- Chang . S.J. . Sims . J. . Murtagh . F.R. . McCaffrey . J.C. . Messina . J.L. . Proliferating Trichilemmal Cysts of the Scalp on CT . American Journal of Neuroradiology . 27 . 3 . 2006-03-01 . 0195-6108 . 16552022 . 712–714 . 7976987 . 2024-05-11.
- Capurso-García . Marino Antonio . Bautista-Piña . Verónica . Pomerantz . Alan . Galnares-Olalde . Javier Andrés . Blachman-Braun . Ruben . Rodríguez-Rodríguez . Sergio . Goldberg-Murow . Monica . Atypical Proliferating Trichilemmal Cyst with Malignant Breast Skin Transformation: A Case Report and Review of the Literature . Case Reports in Oncological Medicine . Hindawi Limited . 2016 . 2016 . 2090-6706 . 10.1155/2016/7481569 . free . 1–4. 27403361 . 4923530 .
- Deshmukh . BhaktiD . Kulkarni . MedhaP . Momin . YasminA . Sulhyan . KalpanaR . Malignant proliferating trichilemmal tumor: A case report and review of literature . Journal of Cancer Research and Therapeutics . 10 . 3 . 2014 . 0973-1482 . 10.4103/0973-1482.136036 . free . 767. 25313781 .
