Malcolm VandenBurg explained

Malcolm VandenBurg is a British doctor involved in drug research, sexual health, medicolegal advice and stress management.^[1]

Medical career

VandenBurg qualified in St Bartholomew's Hospital in 1973 with a BSc in Physiology.

He lectured in medicine, as an Honorary Senior Registrar at the London Hospital and as an Honorary Lecturer in Clinical Pharmacology at St Bartholomew's Hospital

VandenBurg is a Fellow of the Royal College of Physicians, the American College of Clinical Pharmacology and the Faculty of Pharmaceutical Medicine

He established the London Hospital Hypertension Clinic in 1975.^[2]

Research

VandenBurg was director of cardiovascular research, Old Church Hospital Romford (1984–1996) and director of clinical research at Merck Sharpe & Dohme (1980–1984)

In 1996 he was appointed president and chief executive officer of global research consultancy IBRD – Rostrum Inc.^[3]

VandenBurg has coordinated drug development programmes for over 30 pharmaceutical products and has over 100 publications in the field of clinical research.

Medicolegal Work

VandenBurg is a registered expert witness^[4] who has given medicolegal advice to courts, authorities and media in a number of high-profile cases.^[5]

He has written in the BMJ about the medicolegal implications of newer SSRIs^[6] and of driving while under the influence of cannabis^[7]

VandenBurg was an expert witness in the case of the Death of Sean Rigg in police custody in 2008.^[4] He also advised the Northern Ireland Prisoner Ombudsman on the deaths of Aaron Hogg in Maghaberry Prison in 2011.^[8] and Frances McKeown in Hydebank Wood Prison,^[9] both in 2011.

VandenBurg advised the UK press on the use of propofol in the Death of Michael Jackson.^{[10] [11]}

Key Publications

• Johnson . P . Andrews . DC . Wells . S . De Lusignan . S . Robinson . J . Vandenburg . M . The use of a new continuous wireless cardiorespiratory telemonitoring system by elderly patients at home . Journal of Telemedicine and Telecare . 7 Suppl 1 . 5 . 76–7 . 2001 . 11576502 . 10.1258/1357633011936831.
• Dews . I . Vandenburg . M . A 24-week dose-titration study of the angiotensin-converting enzyme inhibitor imidapril in the treatment of mild-to-moderate essential hypertension in the elderly . The Journal of International Medical Research . 29 . 2 . 100–7 . 2001 . 11393342 . 10.1177/147323000102900206. 25326174 .
• Vandenburg. MJ. Mackay, EM . Dews, I . Pullan, T . Brugier, S . Dose finding studies with imidapril--a new ACE inhibitor.. British Journal of Clinical Pharmacology. March 1994. 37. 3. 265–72. 8198936. 1364758. 10.1111/j.1365-2125.1994.tb04274.x.
• Vandenburg. MJ. Allen, ME . Good clinical practice--a question of balance.. British Journal of Clinical Pharmacology. January 1994. 37. 1. 101–2. 8148212. 1364721. 10.1111/j.1365-2125.1994.tb04250.x.
• Vandenburg. MJ. Stephens, JD . Resplandy, G . Dews, IM . Robinson, J . Desche, P . Digoxin pharmacokinetics and perindopril in heart failure patients.. Journal of Clinical Pharmacology. February 1993. 33. 2. 146–9. 8440763. 10.1002/j.1552-4604.1993.tb03935.x. 31434688.
• Allen. ME. Vandenburg, MJ . Good clinical practice: rules, regulations and their impact on the investigator.. British Journal of Clinical Pharmacology. May 1992. 33. 5. 463–5. 1524957. 1381430. 10.1111/j.1365-2125.1992.tb04071.x.
• Wight. LJ. VandenBurg, MJ . Potter, CE . Freeth, CJ . A large scale comparative study in general practice with nitroglycerin spray and tablet formulations in elderly patients with angina pectoris.. European Journal of Clinical Pharmacology. 1992. 42. 3. 341–2. 1577055. 10.1007/bf00266360. 6916899.
• Dews. IM. VandenBurg, MJ . Pullan, TR . A randomized crossover study of the blood pressure effects of tobacco and non-tobacco cigarettes.. Journal of Hypertension Supplement. December 1991. 9. 6. S120–1. 1818907. 10.1097/00004872-199112006-00044.
• Robinson. P. Vandenburg, M . Dews, I . Informed consent.. BMJ (Clinical Research Ed.). 2 November 1991. 303. 6810. 1138. 1747598. 1671252. 10.1136/bmj.303.6810.1138.
• Dews. IM. Vandenburg, MJ . Preventing fraud.. BMJ (Clinical Research Ed.). 13 April 1991. 302. 6781. 907. 1859564. 1669231. 10.1136/bmj.302.6781.907-a.
• Walker. JW. VandenBurg, MJ . Currie, WJ . Differential efficacy of two non-steroidal anti-inflammatory drugs in the treatment of sports injuries.. Current Medical Research and Opinion. 1984. 9. 2. 119–23. 6544198. 10.1185/03007998409109569.
• Hayes. TB. Fyvie, A . Janke, PG . Vandenburg, MJ . Currie, WJ . Sulindac versus ibuprofen in sprains and strains.. British Journal of Sports Medicine. March 1984. 18. 1. 30–3. 6372927. 1858854. 10.1136/bjsm.18.1.30.
• Cooper. WD. Currie, WJ . Vandenburg, MJ . The influence of physicians' instructions on the outcome of antihypertensive therapy.. The British Journal of Clinical Practice. March 1983. 37. 3. 99–103. 6882631.

Books

• Positive Under Pressure jointly authored with Gael Lindenfield, published by Avenue Books (24 April 2006)
• Dilemmas and Solutions in Global Drug Development, published by Brookwood Medical Publications (January 2003)
• Good Clinical Practice for Investigators, ROSTRUM Publications (July 1990)

External links

• Malcolm VandenBurg Official site

Notes and References

1. 10.1136/bmj.b3072 . A controversial career . Careers . BMJ . b3072 . 6 August 2009. Janes . Cath . 79577367 .
2. Book: Stuart R. Walker. Quality of life assessment : key issues in 1990s. 1993. Kluwer. Dordrecht u.a.. 978-0-7923-8991-0. xv–xvi.
3. Web site: The Pharma Letter.
4. Web site: Death of Sean Rigg. IPCC. 5 December 2012. https://web.archive.org/web/20120824080914/http://www.ipcc.gov.uk/Documents/investigation_commissioner_reports/SeanRiggpublication.PDF. 24 August 2012. dead.
5. News: Man disabled by MMR vaccine awarded £90,000 after 13-year fight . https://web.archive.org/web/20100831021829/http://www.telegraph.co.uk/health/healthnews/7970315/Man-disabled-by-MMR-vaccine-awarded-90000-after-13-year-fight.html. dead. 2010-08-31. The Telegraph.
6. Newer antidepressants for the treatment of depression in ad. The BMJ. 17 November 2018.
7. Acute cannabis consumption and motor vehicle collision risk: systematic review of observational studies and meta-analysis. The BMJ. 17 November 2018.
8. Web site: Report by The Prisoner Ombudsman into the circumstances surrounding the death of Aaron Hogg. Northern Ireland Prisoner Ombudsman.
9. Web site: Report by The Prisoner Ombudsman into the circumstances surrounding the death of Frances McKeown. Northern Ireland Prisoner Ombudsman.
10. News: Sedative at centre of Jackson probe . Daily Express.
11. News: Sedative at centre of Michael Jackson 'homicide' probe . The London Evening Standard.