| Country: | MYS |
| Type: | Federal |
| Route: | 500 |
| Length Km: | 163.7 |
| Length Round: | 1 |
| Direction A: | Northwest |
| Terminus A: | Kota Kinabalu |
| Junction: | Federal Route 1 Jalan Penampang Jalan Ranau-Tambunan Kimanis-Keningau Highway Interior North-South Highway Jalan Keningau-Sook |
| Direction B: | Southeast |
| Terminus B: | Tenom (continues as Jalan Tenom-Sipitang) |
| Destinations: | Penampang, Tambunan, Keningau, Sook |
Federal Route 500 (formerly Sabah State Route SA3) is a 163km (101miles) federal highway in Sabah, Malaysia, connecting Kota Kinabalu to Tenom. It serves as the main highway from Kota Kinabalu to towns and villages in the Interior Division of Sabah. Federal Route 500 is one of the five highways in Sabah crossing the Crocker Range; the Tamparuli-Ranau Highway, Kimanis-Keningau Highway and Jalan Tenom-Sipitang are the other three and the new highway, Interior North–South Highway.
While the original Route SA3 is longer, only the section between Kota Kinabalu to Tenom is recommissioned as a federal highway; the section between Tenom to Paal retains its state highway code, while the remaining section from Paal to Kuala Tomani was renumbered as Route SA33 after Jalan Tenom-Sipitang was completed in 2007 and was commissioned as part of Sabah State Route SA3.
| Km | Exit | Interchange | To | Remarks | |
|---|---|---|---|---|---|
| Kota Kinabalu Harbour City | Signalised intersection Start/end of dual-carriageway | ||||
| Kota Kinabalu Sembulan Roundabout | Jalan Mat Salleh Northeast Kota Kinabalu city centre Jalan Penampang Southwest Tanjung Aru | Roundabout | |||
| Tunnel | |||||
| Queen Elizabeth Hospital | Roundabout | ||||
| Taman Waja | Taman Waja | Roundabout | |||
| Kota Kinabalu Jalan Lintas Intersection | Jalan Lintas Northeast Inanam Tuaran Kudat Southwest Tanjung Aru Papar Beaufort | Signalised intersection | |||
| Grand Millennium Plaza | |||||
| Donggongon | Jalan Penampang North Penampang Kota Kinabalu South Lok Kawi | Roundabout End/start of dual-carriageway | |||
| Stadium Penampang | Stadium Penampang Majlis Daerah Penampang Sabah Cultural Center | Roundabout | |||
| Kg. Madasiang | |||||
| Kg. Babagon | Babagon Dam | T-junction | |||
| -- m above sea level | Kota Kinabalu bound, engage lower gear | ||||
| Kipandi Butterfly Park -- m above sea level | |||||
| Gunung Alab R&R complex | R&R complex Kota Kinabalu bound | ||||
| Rafflesia Info Center | Tambunan bound | ||||
| Tambunan Forestry | |||||
| Masakob Waterfall | |||||
| Tambunan bound, Engage lower gear | |||||
| Tambunan Tambunan Roundabout | Jalan Ranau-Tambunan Ranau Kundasang Sandakan | Roundabout | |||
| Tambunan | Tambunan town centre | Roundabout | |||
| Keningau bound, Engage lower gear | |||||
| Apin-Apin | Junctions | ||||
| Keningau District Hospital | Keningau District Hospital | Roundabout | |||
| Keningau | Kimanis-Keningau Highway Northwest Crocker Range National Park Kimanis | Roundabout | |||
| Keningau Jalan Keningau-Sook | Jalan Keningau-Sook Sook Nabawan Kalabakan Tawau | Signalised T-junction | |||
| Jalan Patikang Ulu | Jalan Patikang Ulu Kimanis | T-junction | |||
| Melalap | |||||
| Tenom | Jalan Tenom-Sipitang Ponontomon Sabah Agriculture Park | Roundabout | |||
| Southwest Jalan Tenom-Sipitang Sipitang Sindumin Lawas |