| Makino Tadakuni | |
| Nationality: | Japanese |
| Order: | 12th Daimyō of Nagaoka |
| Term Start: | 1867 |
| Term End: | 1868 |
| Predecessor: | Makino Tadayuki |
| Successor: | Makino Tadakatsu |
| Birth Date: | September 26, 1844 |
| Birth Place: | Edo, Japan |
| Spouse: | Mizuno Tsuneko |
was a Japanese daimyō of the late Edo period, who ruled the Nagaoka Domain. Born the son of Matsudaira Munehide in the Miyazu domain, he was adopted as heir by Makino Tadayuki.
Tadakuni's wife, Tsuneko, recorded a diary of her life in exile after the Boshin War and the fall of Nagaoka Castle.[1] As a traitor against the new government, Tadakuni was voluntarily confined to Shoei-ji in Tokyo. The status of the Nagaoka Domain was restored and endowed to Tsuneko's stepbrother, Makino Tadakatsu.