| Party: | Democratic Alliance (since 2009) |
| Office1: | Member of the National Assembly |
| Termstart1: | June 2003 |
| Termend1: | May 2009 |
| Citizenship: | South Africa |
| Relations: | Frank Mdlalose (father) |
| Birth Date: | 11 April 1957 |
| Otherparty: |
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Makhosazana Mpho Mdlalose (born 11 March 1957) is a South African politician who has served in the National Assembly and KwaZulu-Natal Provincial Legislature, variously representing the Inkatha Freedom Party (IFP), the National Democratic Convention (Nadeco), and the Democratic Alliance (DA).
Mdlalose was born on 11 March 1957.[1] She is the eldest daughter of Frank Mdlalose, the first Premier of KwaZulu-Natal.[2] [3] She joined the IFP in her youth and represented the party in the Newcastle Local Council from 1996 to 2000.[4] By 2003, she was an assistant school principal in Newcastle and the chairman of a local party branch.
In late June 2003, Mdlalose was sworn in to a seat in the National Assembly, filling a casual vacancy in the IFP caucus. She was elected to a full term in her seat in the 2004 general election, standing on the party list for the IFP in KwaZulu-Natal. However, she defected to the newly formed Nadeco on 6 September 2005 during the 2005 floor-crossing window.[5] She subsequently served on Nadeco's national executive committee.[6]
Ahead of the 2009 general election, Mdlalose left Nadeco to join the DA, and in the election she was elected to a DA seat in the KwaZulu-Natal Provincial Legislature.[7] [8]