| Official Name: | Makaryino |
| Native Name: | Макарьино |
| Settlement Type: | Village |
| Pushpin Map: | Russia Vologda Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Vologda Oblast |
| Subdivision Name3: | Sheksninsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 59.0833°N 70°W[1] |
Makaryino (Russian: Макарьино) is a rural locality (a village) in Yurochenskoye Rural Settlement, Sheksninsky District, Vologda Oblast, Russia. The population was 8 as of 2002.[2]
Makaryino is located 22 km south of Sheksna (the district's administrative centre) by road. Sobolevo is the nearest rural locality.[3]