| Official Name: | Makarino |
| Native Name: | Макарино |
| Settlement Type: | Village |
| Pushpin Map: | Russia Vologda Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Vologda Oblast |
| Subdivision Name3: | Nyuksensky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 60.25°N 65°W[1] |
Makarino (Russian: Макарино) is a rural locality (a village) in Gorodishchenskoye Rural Settlement, Nyuksensky District, Vologda Oblast, Russia. The population was 103 as of 2002.[2]
Makarino is located 35 km southeast of Nyuksenitsa (the district's administrative centre) by road. Perkhushkovo is the nearest rural locality.[3]